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New Generation of Nanozyme Based-ToothBleaching Gel with Dual Effect: Tooth Whiteningand Enamel Microhardness Improving


Samira Jafari

Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Iran

Correspondence to Author:  Samira Jafari


Teeth discolouration is one of the most common aesthetic issues caused by inherent or external factors. Patients with severe discolorations may find the bleaching process to be an effective treatment, which can result in an immediate alteration in the colour of their teeth. According to a review of the literature, using commercial products can reduce enamel microhardness because of their high hydrogen peroxide concentration. In light of these problems, the goal of the current scenario is to develop unique, threecomponent dental bleaching solutions based on Cerium Oxide (CeO2) nanozyme that have a dual influence on teeth whitening and augmentation of the microhardness of the enamel. This system is divided into three parts: whitening gel (which contains H2O2), activator gel (which contains CeO2 nanozyme), and supplemental gel (i.e. gel includes hydroxyapatite). On the The synthetic whitening technique has been shown in in vitro and clinical trials to be able to both whiten discoloured teeth and increase microhardness. It’s interesting to note that the clinical case reports for the current study show a striking improvement in tooth colour after using the ready-made in-office whitening dental gel.


Samira Jafari. New Generation of Nanozyme Based-ToothBleaching Gel with Dual Effect: Tooth Whiteningand Enamel Microhardness Improving. Clinical Imaging and Case Reports 2023.

Journal Info

  • Journal Name: Clinical Imaging and Case Reports
  • Impact Factor: 2.709**
  • ISSN: 2770-9205
  • DOI: 10.52338/cicaserep
  • Short Name: CICASEREP
  • Acceptance rate: 55%
  • Volume: 6 (2024)
  • Submission to acceptance: 25 days
  • Acceptance to publication: 10 days


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