Clinical Imaging and Case Reports
Novel Gene Therapies Technology for Spinal CordInjury (SCI) Therapy: Efficient Direct Lineage Reprogramming
Cell Reprogramming and Stem Cell Research Center, Stand up Therapeutics, Korea
Correspondence to Author: Chunggoo Kim
What is understood and the goals: For the past few decades, the definition of spinal cord injury (SCI) has been people becoming wheelchair-bound and requiring lifelong medication . The relatively limited medical options for SCI frequently leaves caretakers feeling more frustrated than before because there is no real cure for the disorder. Yet, due to the enormous amount of research conducted recently, neuroscience has advanced significantly through GT, providing better understanding and raising prospects for neuronal regeneration and functional rehabilitation . Many investigations utilising a synthetic virus (AAV, retro, adeno, or lenti) are opening up interesting research paths as GT technology gains popularity as a viable therapeutic technique [3-5]. We discussed Direct Lineage Reprogramming (DLR) technology in this review.new GT technique for those with SCI.
Chunggoo Kim. Novel Gene Therapies Technology for Spinal CordInjury (SCI) Therapy: Efficient Direct Lineage Reprogramming. Clinical Imaging and Case Reports 2023.