Volume 5 Issue 4 Articles

Quality of Life among Survivors of Brain TumorsVarying by Gender

There are gender disparities in the long-term effects of brain tumours on quality of life (QOL), and bare bones research. Methods: QOL measurements were evaluated in 81 individuals with brain tumours…

Improving the Efficacy of Cisplatin in Colon Cancer HT– 29 Cells via Combination Therapy withSelenium

In general, cis-platinum is ineffective in treating slow-growing colon cancer. A seleno-enzyme that neutralises reactive oxygen species is glutathione peroxidase (ROS). High ROS concentrations may affect the efficacy of cisplatinum…

Doravirine and Rilpivirine Intra Cellular Accumulation in the Clinical Setting

The NNRTIs currently used most frequently in clinical settings, in dual and triple medication regimens (2DR and 3DR), are doravirine (DOR) and rilpivirine (RPV). These medicines’ intracellular (IC) pharmacokinetics (PK) are not yet well understood…

Distribution of TRPV1 in the Rat Brain Parenchyma’s CSF Contacting Nucleus and its Expressionin Neuropathic Pain

The ventral periaqueductal central grey (PAG) of the brainstem is home to the cerebrospinal fluidcontacting nucleus (CSF-CN), which may affect the actual composition of the cerebrospinal fluid (CSF) for non-synaptic signal transmission by releasing or absorbing bioactive material…